Ultraviolet Blood Irradiation Clinical Trial


We are now offering UVLRx as part of an FDA investigational trial studying the effectiveness on patients with chronic fatigue. 

Housed within our UVLrx Station is an optic engine which is delivered through the Patient Cable  and which integrates with the distal end of our patent-pending Dry Light Adapter (DLA) .  The DLA feeds an optical filament into a 20-gauge intravascular catheter  to provide direct treatment of the blood.  During the treatment, normal saline solution flows through the DLA via the saline entry connector  preventing light attenuation within the catheter.

In a typical UVLRx treatment three separate wavelengths are delivered to the patient.  Each wavelength activates a specific biochemical pathway, with their concurrent powerful and therapeutic effect being the  benefit of the UVLrx.  

Clinical trials:

Chronic Fatigue

Certificate of Training

There has been critizism by some not familair with the science behind this treatment. Below are some Peer Reviewed journal articles on the safety and mechanisms of action for UV treatment of the blood for the chronic fatigue study.

1. Jackson A (1997) Performing peripheral intravenous cannulation. Professional Nurse. 13, 1, 21-25.

2. Wilson, J. (2006) Preventing infection associated with intravascular therapy In: Infection Control in Clinical Practice 3rd ed. Baillière Tindall London 199–213.

3. Blum A. Immediate recovery of an "ischemic stroke" following treatment with intravenous thiamine (vitamin B1). Isr Med Assoc J. 2014 Aug;16(8):518-9.

4. Patil S. Intravenous β-artemether formulation (ARM NLC) as a superior alternative to commercial artesunate formulation. J Antimicrob Chemother. 2012 Nov;67(11):2713-6.

5. Lei Y. Ventilator-associated tracheobronchitis: pre-emptive, appropriate antibiotic therapy recommended. Crit Care. 2014 Nov 19; 18(6):627.

6. Miller, V. Hydration, Hydration, Hydration. Ann Occup Hyg. 2010 Mar;54(2):134-6.

7. Wendt D. Thermoregulation during exercise in the heat: strategies for maintaining health and performance. Sports Med. 2007;37(8):669-82.

8. Knowles JR (1980). "Enzyme-catalyzed phosphoryl transfer reactions".Annu. Rev. Biochem. 49: 877– 919.

9. Huang YY. Biphasic Dose Response in Low Level Light Therapy. Dose Response. 2009; 7(4): 358– 383.

10. Karu T. Mitochondrial Signaling in Mammalian Cells Activated by Red and Near-IR Radiation. Photochemistry and Photobiology, 2008, 84: 1091-1099.

11. Karu, T. I. Photobiology of low-power laser effects. Health Phys. 1989, 56, 691–704.

12. Brunori M. Cytochrome c oxidase, ligands and electrons. J Inorg Biochem. 2005 Jan;99(1):324-36.

13. Passarella S, Pastore D. Increase of proton electrochemical potential and ATP synthesis in rat liver mitochondria irradiated in vitro by helium-neon laser. FEBS Lett. 1984 Sep 17;175(1):95-9.

14. Karu TI, Piatibrat LV. Changes in the amount of ATP in HeLa cells under the action of He-Ne laser radiation. Biull Eksp Biol Med. 1993 Jun;115(6):617-8.

15. Wong-Riley MT, Whelan HT. Light-emitting diode treatment reverses the effect of TTX on cytochrome oxidase in neurons. Neuroreport. 2001 Oct 8;12(14):3033-7.

16. Pastore D, Passarella S. Specific helium-neon laser sensitivity of the purified cytochrome c oxidase. Int J Radiat Biol. 2000 Jun;76(6):863-70.

17. Eells JT, Wong-Riley MT. Mitochondrial signal transduction in accelerated wound and retinal healing by near-infrared light therapy. Mitochondrion. 2004 Sep;4(5-6):559-67.

18. Castro-e-Silva T. The use of light-emitting diodes to stimulate mitochondrial function and liver regeneration of partially hepatectomized rats. Brazilian Journal of Medical and Biological Research (2007) 40: 1065-1069.

19. Wong-Riley MT, Liang HL, Eells JT, Chance B, Henry MM, et al. Photobiomodulation directly benefits primary neurons functionally inactivated by toxins: role of cytochrome c oxidase. J Biol Chem. 2005; 280(6):4761–4771.

20. Hamblin MR, Tatiana ND. Mechanisms of low level light therapy. Proc. SPIE 6140, Mechanisms for Low-Light Therapy, 614001 (February 10, 2006)

21. Kassak P, Przygodzki T. Mitochondrial alterations induced by 532nm laser irradiation. Gen. Physiol. Biophys. (2005), 24, 209-220.

22. P. KAŠŠÁK, L. ŠIKUROVÁ, P. KVASNIČKA, M. BRYSZEWSKA. The Response of Na+/K+- ATPase of Human Erythrocytes to Green Laser Light Treatment. Physiol. Res. 55: 189-194, 2006.

23. Müller-Enoch D. Blue light mediated photoreduction of the flavoprotein NADPH-cytochrome P450 reductase. A Förster-type energy transfer. Z Naturforsch C. 1997 Sep-Oct;52(9-10):605-14.